The Mechanism Of Mounjaro: How It Aids In Weight Loss

Mounjaro is emerging as one of the most effective injectable medications for weight loss, but what makes it stand out from other treatments? We spoke to our experts here at Levity to find out more.

Understanding the Basics: How Does Mounjaro Work?

Mounjaro is a gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) medication that, unlike other weight loss treatments, mimics two weight loss boosting hormones instead of one. This dual-action approach can help people lose up to 20% of their body weight after 72 weeks with diet and exercise. [1] In comparison, single-acting hormone medications like Wegovy and Ozempic typically result in an average weight loss of 15% and 7% respectively. [2]

How Does Mounjaro Work For Weight Loss?

Appetite regulation

Mounjaro controls appetite regulation and blood sugar levels. It’s designed to address the complex interplay of hormones and neurotransmitters involved in hunger signalling. [3]

Improving fullness

By stimulating receptors in the gut and signalling to the brain that you've had enough to eat, Mounjaro makes you feel more full and satisfied, which leads to less calorie consumption. [3]

Supporting portion control

Thanks to Mounjaro's appetite-regulating effects, many people find portion control is much easier. Rather than overindulging, many people may find it easier to stick to their set meal plans, leading to consistent progress towards their weight loss goals. [3]

How Much Weight Do People Lose With Mounjaro?

In the most recent clinical trials, patients lost up to 20% of their original body weight after a year, in combination with diet changes and increased physical activity. [4]

Is Mounjaro Right For Me?

At Levity, we only prescribe Mounjaro to people with a BMI (body mass index) of 30, or 27 for people with certain weight-related medical conditions, such as heart disease or high blood pressure. Weight loss injections aren't suitable for anyone with a history of eating disorders, or during pregnancy. 

Potential common side effects include allergic reactions at the site of injection, or other adverse effects such as gastrointestinal problems. These side effects are common, mild, and should fade with time.

Learn More About Weight Loss Medications

At Levity, our expert team understands the challenges people face when it comes to weight loss. That's why we've developed a comprehensive treatment plan for achieving and maintaining a healthy weight, with support for everything from diet and exercise to common side effects. You can learn more about Mounjaro and other GLP-1 receptor medications at joinlevity.co.uk.

References

1. FDA. FDA Approves New Medication for Chronic Weight Management [Internet]. FDA. 2023. Available from: https://www.fda.gov/news-events/press-announcements/fda-approves-new-medication-chronic-weight-management 
2. Davies M, Færch L, Jeppesen OK, Pakseresht A, Pedersen SD, Perreault L, et al. Semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial. The Lancet [Internet]. 2021 Mar;397(10278):971–84. Available from: https://pubmed.ncbi.nlm.nih.gov/33667417/ 
3. Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, et al. Tirzepatide Once Weekly for the Treatment of Obesity. New England Journal of Medicine [Internet]. 2022 Jun 4;387(3). Available from: https://www.nejm.org/doi/full/10.1056/NEJMoa2206038 
4. Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, et al. Tirzepatide Once Weekly for the Treatment of Obesity. New England Journal of Medicine [Internet]. 2022 Jun 4;387(3). Available from: https://www.nejm.org/doi/full/10.1056/NEJMoa2206038